The Ham test, or acidified serum lysis test, is performed to determine the cause of undiagnosed hemolytic anemia, hemoglobinuria, and bone marrow aplasia. This test determines the stability of the red blood cell (RBC) membrane. It helps establish a diagnosis of paroxysmal nocturnal hemoglobinuria (PNH), a rare hematologic disease.
Procedure And Posttest Care
Normally, RBCs don't undergo hemolysis. Test results should be negatives.
Hemolysis of RBCs indicates PNH.
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